Drug Development
The Angiogenesis Research Center offers a turn key approach to angiogenic and myogenesis development with the bench to bedside paradigm. The Center provides rapid in vitro testing of novel angiogenic cytokines, transcriptional factors, and cells leading to in vivo models. In vivo models include the mouse matrigel model, mouse and rat myocardial infarction and hind limb ischemia model, rabbit hindlimb ischemia model, and porcine (normal and diseased) myocardial ischemia models. This is followed by assistance with IND/IDE submission and pilot clinical trial design and execution. This enables rapid bench to bedside evaluation of promising compounds.